Get in touch!
What did you like? What can I do better? What would you love me to answer on the show? Or just say hi.
Email: orlando@modifiedpod.com
Instagram: @seattleplantnerd
Bluesky: @orlandodl
Join me as we dig into a heaped serving of GMO crops through the lens of science, history, and culture. From the Victorian origins of plant genetics through to the genetically modified world we live in today. I’m Orlando de Lange and I’ll be your guide as we explore (true) stories that just might change how you think about the food on your plate, and the future of agriculture.
What did you like? What can I do better? What would you love me to answer on the show? Or just say hi.
Email: orlando@modifiedpod.com
Instagram: @seattleplantnerd
Bluesky: @orlandodl

7 days ago
7 days ago
Ant plants, Chameleon plants, and skinny-peel mangoes. Let's dive into your questions and I'll do my best to answer them.
References
Leaf Mimicry in a Climbing Plant Protects Against Herbivory - Gianoli & Carrasco-Urra - Current Biology, 2014
Boquila trifoliata Mimics Leaves of an Artificial Plastic Host Plant - White & Yamashita - Plant Signaling & Behavior, 2021
Endophytic Bacterial Communities are Associated with Leaf Mimicry in the Vine Boquila trifoliata - Gianoli et al. - Scientific Reports, 2021
How the Tulip Breaking Virus Created Striped Tulips - Wong, Carrero & Hillen - Communications Biology, 2025
Start of the Art of Dahlia Breeding - A dissertation by Karen Renae Bender - Iowa State University, 2022
The Genome Evolution and Domestication of Tropical Fruit Mango - Wang et al. - Genome Biology, 2020

Saturday Nov 01, 2025
Saturday Nov 01, 2025
How do plants defend themselves, fighting a war of attrition cell by cell? And how did a scientist in Minnesota in the 1950s reshape how we understand plant immune systems and the genetics at their heart. And of course, how does this all connect to GMOs? Let's find out.
References
H. H. FLOR: PIONEER IN PHYTOPATHOLOGY
Jin L, Chen M, Xiang M, Guo Z. RNAi-Based Antiviral Innate Immunity in Plants. Viruses. 2022 Feb 20;14(2):432.
FAO. 2022. FAO’s Plant Production and Protection Division. Rome.
PAPAYA RINGSPOT VIRUS (PRY): A SERIOUS DISEASE OF PAPAYA
2024 STATE AGRICULTURE OVERVIEW - Hawaii

Saturday Oct 18, 2025
Saturday Oct 18, 2025
What are these little bundles of DNA we call genes and how does a bunch of genes work together to make a whole plant? In this episode we’ll take a journey through plant genetics and see why scientists have been so keen to unlock these secrets and ultimately to shape them to human ends.
References:
On the history of Japanese rice research in Taiwan:
Tracing the Roots of Taiwanese Rice. Cathy Teng, photos Chuang Kung-ju, tr. by Scott Williams July 2016
Leow, W.Y. (2020). Horai Rice in the Making of Japanese Colonial Taiwan. Cross-Currents: East Asian History and Culture Review 9(1), 40-66.
Wikipedia: Taiwan Under Japanese Rule
On Gibberellin research
Hedden, P., Sponsel, V. A Century of Gibberellin Research. J Plant Growth Regul 34, 740–760 (2015). https://doi.org/10.1007/s00344-015-9546-1
RADLEY, M. Occurrence of Substances Similar to Gibberellic Acid in Higher Plants. Nature 178, 1070–1071 (1956). https://doi.org/10.1038/1781070a0
Bernard O Phinney. By Ann Hirsch. UCLA Department of Ecology and Evolutionary Biology.

Saturday Oct 04, 2025
Saturday Oct 04, 2025
Around the same time as Miescher was tinkering with DNA in Tubingen castle, a middle aged friar-scientist Gregor Mendel was experimenting with inheritance of pea plants. He was the first to define a set of mathematical rules behind inheritance that birthed the field of genetics - a field that lay dormant for a few decades before exploding in the 1900s, and continues to develop to this day. Genetics gives us the tools to reshape the living world with intention and at speed.
References:
1. Versuche über Pflanzenhybriden. Zwei Abhandlungen. (1865 und 1869.) Von Gregor Mendel. Herausgegeben von Erich Tschermak [Experiments in Plant Hybridization. Two Treatments. (1865 and 1869). By Gregor Mendel. Published by Erich Tschermak. https://babel.hathitrust.org/cgi/pt?id=hvd.hs118q&seq=7
2. Gregor Mendel and his Precusors. Conway Zirkle. 1951. https://www.jstor.org/stable/226964?seq=1
3. Bateson W. (1906) "The progress of genetic research" Report of the Third International Conference 1906 on Genetics, W. Wilks, ed. London, England: Royal Horticultural Society. https://www.biodiversitylibrary.org/item/206746#page/129/mode/1up
4. Fairbanks, D.J. Demystifying the mythical Mendel: a biographical review. Heredity 129, 4–11 (2022). https://www.nature.com/articles/s41437-022-00526-0

Saturday Sep 20, 2025
Saturday Sep 20, 2025
Genes can be a metaphor for our sense of self. But they are also real, physical, things made up of DNA parts, locked inside the cells of every living organism. In this episode we explore the materiality of genes, as well as some of the human stories behind the science.
References:
Waclaw Szybalski on Martha Chase - Cold Spring Harbor laboratory - Oral history collections.
Martha Chase at the University of Rochester: The Woman in STEM Who Was Forgotten. The Journal of Undergraduate Research - University of Rochester. Spring 2024, Volume 22, Issue 2. Michelle A. Bischoff ‘24, Xuke Wang, Erin Song, Gabrielle Wilson, Monica Brody, Suchi Iyer, Kirya Caine, and Michael Clark*

Saturday Sep 06, 2025
Saturday Sep 06, 2025
The roots of today’s genetically modified world stretch back two centuries, to a castle kitchen in Southern Germany. This episode will set the stage for our whole podcast introducing key themes and foundational concepts of genetics and molecular biology.

Monday Aug 04, 2025
Monday Aug 04, 2025
Everything you wanted to know about GMO crops and hopefully a lot of things you would have never thought to ask. Announcing Modified, a new podcast by Dr. Orlando de Lange - plant scientist, biotechnology educator, and lover of podcasts.
This announcement episode briefly introduces the podcast and lets you know what to expect.